The population of breast cancer cells that gives rise to a tumor may be relatively resistant to radiotherapy and may even increase when given multiple treatments of radiation, a new study shows.In the last several years, researchers have discovered a small population of so-called cancer-initiating cells (also called cancer stem cells) in several cancers. These cells can self-renew and maintain the growth of a tumor, whereas its daughter cells cannot. [click link for full article]

A recent paper by Y. Osman, T. El-Diasty and colleagues from Mansoura Egypt examined the role of magnetic imaging urethrography (MR RUG) in the management of urethral strictures. The manuscript is published in the September 2006 issue of European Urology.Over a 4 month period in 2004, 20 patients referred to the authors for management of urethral stricture disease were evaluated with conventional retrograde urethrography (RUG) and multiformat MR urethrography. [click link for full article]

UroToday.com - A serum PSA increase of 2 ng/ml or greater the year before prostate cancer diagnosis has recently been associated with a higher risk of prostate cancer elated death. The association between cancer-related death and PSA velocity decades before diagnosis (with values significantly below 4.0 ng/ml) has not been well established. [click link for full article]

UroToday.com - Dr.⬔s Hwang Choi from South Korea and Katsuya Nonomura from Japan chaired the instructional course focusing on surgical tips for urethroplasty. The faculty included Gerry Jordan from Norfolk Virginia, Wachira Kochakarn from Thailand, Jack McAninch from San Francisco, and Christopher Chapple from The UK.The session started with Dr. Kochakarn⬔s discussion on the surgical management of female urethral diverticulum. The incidence of a urethral diverticulum is 1. [click link for full article]

UroToday.com - Osteopontin (OPN) is a phosphorylated glycoprotein that is secreted into the extracellular matrix by a variety of cell types and has diverse functions which include enhancement of tumorigenesis and tumor progression in a variety of human tumors. Here, Matusan and colleagues examine the expression of OPN in human clear cell renal cell carcinoma (RCC). The authors performed immunohistochemistry for OPN on 171 specimens of clear cell RCC. [click link for full article]

UroToday.com - Despite the number of radical prostatectomies performed around the world, the role of adjuvant radiotherapy in the management of patients with locally advanced prostate cancer remains controversial. In the November 15th issue of JAMA, Thompson and colleagues report the results of a prospective randomized trial designed to determine the role of radiation therapy in patients with pathologically advanced prostate cancer after radical prostatectomy. [click link for full article]

UroToday.com - Aspiration and sclerosis remain the primary management for symptomatic simple renal cysts. However, as these investigators have shown, laparoscopic decortication is the management of choice for those cysts too large to be managed by aspiration or for those that are recurrent. [click link for full article]

Two years after the raging waters of the tsunami swept away lives, homes and communities in more than a dozen countries, daily routines are slowly coming back for those impacted by this disaster. However, for many people struggles persist. It is widely acknowledged that the greatest needs are for housing and livelihoods. [click link for full article]

The results of the second survey of continence care for older people carried out by the Royal College of Physicians show little improvement since this time last year. There have been minor improvements in some areas, but integrated services are still a dream rather than a reality. Urinary incontinence affects some 24% of older people and 30-60% of people in institutional care. [click link for full article]

Adams Respiratory Therapeutics, Inc. (Nasdaq: ARxT) today announced that it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for 600 mg and 1200 mg oral solid extended-release guaifenesin combination products for the treatment of cough. This new drug represents the first prescription product in Adams’ current portfolio of respiratory products. [click link for full article]