February 17, 2008
There are two major classes of prescription nasal sprays available for the treatment of allergic rhinitis: Nasal steroids (such as Flonase, Nasonex, Rhinocort, Nasacort and Veramyst) and nasal antihistamines (Astelin)….
Despite an ageing population, outcomes for coronary artery bypass graft (CABG) surgery patients in Victoria remained steady between 2001 and 2006, and 30-day mortality rates are still low, according to a study published in the latest Medical Journal of Australia.
The question of whether it is appropriate to vaccinate older women against Human papillomavirus (HPV) is presented for debate in the latest issue of the Medical Journal of Australia.
Canadians are being advised not to use 25 mcg/hr Duragesic (fentanyl transdermal system) patches (Janssen-Ortho Inc.) and 25 mcg/hr Ran Fentanyl Transdermal System patches (Ranbaxy). The manufacturers are voluntarily recalling Duragesic and Ran Fentanyl Transdermal System 25 mcg/hr patches as it is possible they may have a cut along one side, raising the risk of the fentanyl gel leaking from the patch.
We all know that drinking and driving is dangerous and can lead to serious injury and loss of life. However, fewer people are aware of the significant of danger of driving while drowsy. If you drive while you are drowsy your reflexes are severely impaired, as are your senses of awareness and judgment. According to studies, if you drive after not sleeping for 18 hours your senses are undermined to the same level as somebody whose blood alcohol level is 0.05%.
Two previously unconnected cancer-promoting proteins team up to ambush a critical tumor suppressor by evicting it from the cell’s nucleus and then marking it for death by a protein-shredding mechanism, a team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in Nature Cell Biology.
If the genome is the parts list of the human cell, certain proteins are the production managers, activating and deactivating genes as needed. Scientists funded by the National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health, now have a clearer understanding of how a key protein controls gene activity and how mutations in the protein may cause disease. The work could provide new avenues to design drugs aimed at cancer, diabetes, HIV, and heart disease.
UroToday.com - This is an extremely important report of the importance of preserving as much normal functioning renal tissue as possible when treating patients with renal tumor disease. These researchers at UT Southwestern clearly demonstrate that in all patients presenting with renal tumors almost a third will have pre-existing compromise of their renal function to stage 3 chronic kidney disease (CKD) as defined by a GFR
UroToday.com- This article further strengthens the argument that an extended lymph node dissection improves staging accuracy and survival in patients with invasive bladder cancer. Investigators at two different institutions (Cleveland Clinic and University of Bern) evaluated their long-term outcomes after radical cystectomy and pelvic lymph node dissection.
UroToday.com - Dr. Sandler reported on a secondary analysis of RTOG 85-31, in which the patients who got longer duration of ADT had better survival. In RTOG 9202, 1,554 men with T3 disease had either ADT for a mean of 28 months vs. short term ADT and there was a PCSM benefit to long term therapy. The benefit is seen most in high-risk patients. In the Harvard trial updated by D’Amico, there is a persistent PCSM advantage to those who received 6 months ADT vs. no ADT.