Traumatic brain injury expert Gerard Gioia, PhD, Chief of Neuropsychology at Children’s National Medical Center and director of the

By injecting a customized “genetic patch” into early stage fish embryos, researchers at Washington University School of Medicine in St. Louis were able to correct a genetic mutation so the embryos developed normally.The research could lead to the prevention of up to one-fifth of birth defects in humans caused by genetic mutations, according to the authors.Erik C. Madsen, first author and an M.D./Ph.D.

For many of the nation’s 40 million contact lens wearers, seasonal ocular allergy symptoms such as itching, tearing, and redness caused by contact lens wear, often hit them during the time that they want to be wearing their lenses for outdoor sports, exercise, and socializing. This increase in incidences of lens discomfort causes many to use rewetting drops more often, wear their lenses less frequently, or switch back to glasses.

UroToday.com - Various surgical techniques are available for nephron-sparing surgery (NSS) in patients with renal cell carcinoma (RCC). However, the size of surgical margin that should be removed with tumor remains controversial. Resection of the tumor with excision of a margin of 1 cm of normal-appearing parenchyma around the tumor has been considered as the standard surgical technique in NSS for many years.

Hyperactive young girls are more likely to have poor school-leaving qualifications, become hooked on smoking and fall into mentally abusive relationships later in life, according to a collaborative study led by UCL (University College London) and the University of Montreal.

UroToday.com - Interstitial cystitis (IC) is not “one disease.” It is a sum of many different symptoms, and every patient needs to be treated as unique. Success can be achieved only if there is good collaboration between the patient, who needs to make lifestyle changes, the physicians and physical therapists.What IC patients have in common is varying degrees of voiding dysfunction. They are miserable, and often no one has acknowledged that they have a real problem.

UroToday.com - Intravesical Potassium Chloride Screening Positive In 32.8% of Female Turkish Textile WorkersHow many unselected women in a population would have a BPS/IC if one considers a positive KCl test as a definitive standard? Six years ago Parsons answered this question for an American population1, determining that 74% of women with a pelvic pain, frequency, urgency scale (PUF) of 10-14 will have a positive potassium test.

UroToday.com - This is a study from Gujarat, India regarding transperitoneal laparoscopic pyeloplasty in children. This group reported their technique and outcome with laparoscopic transperitoneal dismembered pyeloplasty in the pediatric population. They had 19 patients ranging from 2-14 years of age who underwent laparoscopic pyeloplasty between June 2004 and December 2006. Of the 19 patients 13 pyeloplasties were performed on the left and 6 on the right.

UroToday.com - A prospective study out of France evaluated the effectiveness of antibiotic prophylaxis in reducing the incidence of urinary tract infections in young children with low-grade vesicoureteral reflux, Grade I through Grade III. The group randomly assigned children 1 month to 3 years of age with Grade I to Grade III vesicoureteral reflux randomly to receive cotrimoxazole or no treatment. They followed these patients for 18 months.

UroToday.com - In the online version of the FASEB Journal, Dr. Kelly and associates from Memorial Sloan-Kettering Cancer Center report that oncolytic therapy using HSV engineered to minimize neurotoxicity holds clinical promise. Herpes oncolytic vectors are effective gene transfer agents with attenuated toxicity to normal cells. These are replication competent viruses that have potent antitumor activity by inducing direct tumor cell lysis.