UroToday.com - Despite the number of radical prostatectomies performed around the world, the role of adjuvant radiotherapy in the management of patients with locally advanced prostate cancer remains controversial. In the November 15th issue of JAMA, Thompson and colleagues report the results of a prospective randomized trial designed to determine the role of radiation therapy in patients with pathologically advanced prostate cancer after radical prostatectomy. [click link for full article]